|
KMID : 0854720070270020125
|
|
Korean Journal of Asthma, Allergy and Clinical Immunology
2007 Volume.27 No. 2 p.125 ~ p.130
|
|
|
Evaluation of the Causes of Chronic Cough with Sputum Eosinophilia
|
|
Sohn Seong-Wook
Yang Min-Suk
Lee So-Hee
Song Woo-Jung
Lee Sang-Min
Kwon Hyouk-Soo
Kim Deok-In
Park Chang-Han
Park Heung-Woo
Chang Yoon-Seok
Kim Sun-Sin
Cho Sang-Heon
Min Kyung-Up
Kim You-Young
|
|
|
Abstract
|
|
|
Background: Eosinophilic bronchitis (EB) is recently regarded as an important cause of chronic cough. However, sputum eosinophilia is commonly encountered in the other causes of chronic cough such as upper airway cough syndrome (UACS) and asthma.
Objective: To evaluate the cause of chronic cough with sputum eosinophilia.
Method: We investigated patients with chronic cough. Induced sputum, methacholine bronchial provocation test, skin prick test, throat examination, chest X-ray, paranasal sinus (PNS) x-ray and rhinoscopy were performed.
Result: Sputum was induced in 287 patients. Sputum eosinophilia greater than 3% was present in 117 (40.8%) patients. Among 117 patients with sputum eosinophilia, eosinophilic asthma was diagnosed in 36 (30.8%) patients, chest X-ray abnormality or ACEI use was detected in 18 (15.4%) patients, and the remaining 63 (53.8%) patients could be considered to have EB. Among 63 patients with EB, UACS and GERD were found to be combined in 48 (76.2%) and 2 (3.2%) patients, respectively. EB alone without the other causes was diagnosed in 13 (11.1%) patients. Among total 287 patients, EB was detected in 22.0%, and EB alone without the other causes in 4.5%.
Conclusion: Sputum eosinophilia can be frequently detected in chronic cough. EB is the common cause in chronic cough with sputum eosinophilia. However, EB is likely to be associated with UACS, which should be considered in cases of EB. (Korean J Asthma Allergy Clin Immunol 2007;27:125-130)
|
|
|
KEYWORD
|
|
|
Chronic cough, Sputum eosinophilia, Eosinophilic bronchitis, UACS, Asthma
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
  
|
|